Otters can be discouraged from areas by sealing existing den sites and water impoundment outlets (i.e., culverts, drainage pipes, etc.). The sealing of water impoundment outlets should be done to allow water flow, but exclude otters. Fish loss from otters can be reduced by providing fish escape options from predation, thus increasing the difficulty for otters to catch them. This can be done by maintaining aquatic vegetation and placing brush or other structures in the water impoundment or pond to provide fish a place to hide.

Electric fencing or netting is also an option, but it is often too expensive or impractical for larger areas. If using electric fence, use at least 4 strands, spaced 4-5 inches apart. These strands should be tight and clear of weeds to prevent grounding. The bottom wire should also be low to the ground. The goal is to make spacing between strands small enough that an otter cannot pass through without getting shocked.

Otter removal may be necessary if damages are significant. Relocation is rarely the best solution because otters have to be moved long distances to prevent their return. In addition, the moving of wildlife should be done carefully and according to local regulations, as diseases and parasites travel with their host and may infect more individuals and spread disease. In areas where otter populations are high, understand that removing one otter may mean a new one moves in to take its place quickly.